Research Progress on Natural Small-Molecule Compounds for the Prevention and Treatment of Sepsis

Sepsis is a serious disease with high mortality and has been hot research topic in medical recent years. With the continuous reporting of in-depth on pathological mechanisms sepsis, various compounds have developed to prevent treat sepsis. Natural small-molecule play vital roles prevention treatment sepsis; for example, such as resveratrol, emodin, salidroside, ginsenoside, others can modulate signaling through NF-κB, STAT3, STAT1, PI3K, other pathways relieve inflammatory response, immunosuppression, organ failure caused by Here, we discuss functions natural preventing treating This review will lay theoretical foundation discovering new that potentially